PT - JOURNAL ARTICLE AU - Yina Du AU - Minzhe Guo AU - Jeffrey A Whitsett AU - Yan Xu TI - ‘LungGENS’: a web-based tool for mapping single-cell gene expression in the developing lung AID - 10.1136/thoraxjnl-2015-207035 DP - 2015 Nov 01 TA - Thorax PG - 1092--1094 VI - 70 IP - 11 4099 - http://thorax.bmj.com/content/70/11/1092.short 4100 - http://thorax.bmj.com/content/70/11/1092.full SO - Thorax2015 Nov 01; 70 AB - We developed LungGENS (Lung Gene Expression iN Single-cell), a web-based bioinformatics resource for querying single-cell gene expression databases by entering a gene symbol or a list of genes or selecting a cell type of their interest. Gene query provides quantitative RNA expression of the gene of interest in each lung cell type. Cell type query returns associated selective gene signatures and genes encoding cell surface markers and transcription factors in interactive heatmap and tables. LungGENS will be broadly applicable in respiratory research, providing a cell-specific RNA expression resource at single-cell resolution. LungGENS is freely available for non-commercial use at https://research.cchmc.org/pbge/lunggens/default.html.