RT Journal Article SR Electronic T1 A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial JF Thorax JO Thorax FD BMJ Publishing Group Ltd and British Thoracic Society SP 1054 OP 1061 DO 10.1136/thoraxjnl-2015-207032 VO 70 IS 11 A1 Valentina Isetta A1 Miguel A Negrín A1 Carmen Monasterio A1 Juan F Masa A1 Nuria Feu A1 Ainhoa Álvarez A1 Francisco Campos-Rodriguez A1 Concepción Ruiz A1 Jorge Abad A1 Francisco J Vázquez-Polo A1 Ramon Farré A1 Marina Galdeano A1 Patricia Lloberes A1 Cristina Embid A1 Mónica de la Peña A1 Javier Puertas A1 Mireia Dalmases A1 Neus Salord A1 Jaime Corral A1 Bernabé Jurado A1 Carmen León A1 Carlos Egea A1 Aida Muñoz A1 Olga Parra A1 Roser Cambrodi A1 María Martel-Escobar A1 Meritxell Arqué A1 Josep M Montserrat A1 the SPANISH SLEEP NETWORK YR 2015 UL http://thorax.bmj.com/content/70/11/1054.abstract AB Background Compliance with continuous positive airway pressure (CPAP) therapy is essential in patients with obstructive sleep apnoea (OSA), but adequate control is not always possible. This is clinically important because CPAP can reverse the morbidity and mortality associated with OSA. Telemedicine, with support provided via a web platform and video conferences, could represent a cost-effective alternative to standard care management.Aim To assess the telemedicine impact on treatment compliance, cost-effectiveness and improvement in quality of life (QoL) when compared with traditional face-to-face follow-up.Methods A randomised controlled trial was performed to compare a telemedicine-based CPAP follow-up strategy with standard face-to-face management. Consecutive OSA patients requiring CPAP treatment, with sufficient internet skills and who agreed to participate, were enrolled. They were followed-up at 1, 3 and 6 months and answered surveys about sleep, CPAP side effects and lifestyle. We compared CPAP compliance, cost-effectiveness and QoL between the beginning and the end of the study. A Bayesian cost-effectiveness analysis with non-informative priors was performed.Results We randomised 139 patients. At 6 months, we found similar levels of CPAP compliance, and improved daytime sleepiness, QoL, side effects and degree of satisfaction in both groups. Despite requiring more visits, the telemedicine group was more cost-effective: costs were lower and differences in effectiveness were not relevant.Conclusions A telemedicine-based strategy for the follow-up of CPAP treatment in patients with OSA was as effective as standard hospital-based care in terms of CPAP compliance and symptom improvement, with comparable side effects and satisfaction rates. The telemedicine-based strategy had lower total costs due to savings on transport and less lost productivity (indirect costs).Trial register number NCT01716676.