RT Journal Article SR Electronic T1 The utility of ultrasound-guided thoracentesis and pleural biopsy in undiagnosed pleural exudates JF Thorax JO Thorax FD BMJ Publishing Group Ltd and British Thoracic Society SP 995 OP 997 DO 10.1136/thoraxjnl-2014-206567 VO 70 IS 10 A1 Koegelenberg, Coenraad Frederik N A1 Irusen, Elvis Malcom A1 von Groote-Bidlingmaier, Florian A1 Bruwer, Johannes Willem A1 Batubara, Enas Mansour A A1 Diacon, Andreas Henri YR 2015 UL http://thorax.bmj.com/content/70/10/995.abstract AB We assessed the utility of ultrasound to guide the selection of closed pleural biopsy technique and site and to assess the respective contributions of repeat thoracentesis and closed pleural biopsy in 100 consecutive patients with undiagnosed pleural exudates. Thoracentesis was more likely to be diagnostic in TB than malignancy (77.8% vs 31.0%, p<0.001). The addition of ultrasound-guided biopsy increased the combined yield for all diagnoses from 48.0% to 90.0% (p<0.001), for malignancy from 31.0% to 89.7% (p<0.001) and for TB from 77.8% to 88.9% (p=0.688). Our findings suggest that this minimally invasive approach has a high diagnostic yield.