PT  - JOURNAL ARTICLE
AU  - J R Stradling
AU  - S E Craig
AU  - M Kohler
AU  - D Nicoll
AU  - L Ayers
AU  - A J Nunn
AU  - D J Bratton
TI  - Markers of inflammation: data from the MOSAIC randomised trial of CPAP for minimally symptomatic OSA
AID  - 10.1136/thoraxjnl-2014-205958
DP  - 2015 Feb 01
TA  - Thorax
PG  - 181--182
VI  - 70
IP  - 2
4099  - http://thorax.bmj.com/content/70/2/181.short
4100  - http://thorax.bmj.com/content/70/2/181.full
SO  - Thorax2015 Feb 01; 70
AB  - The Multi-centre Obstructive Sleep Apnoea Interventional Cardiovascular (MOSAIC) trial compared 6 months of CPAP therapy, versus no CPAP, in 391 patients with minimally symptomatic obstructive sleep apnoea (OSA). We now report some exploratory outcomes, markers of systemic inflammation (interleukin 6 (IL-6), IL-10, C reactive protein, tumour necrosis factor). We found no consistent changes (all p values >0.13). Trial registration number: ISRCTN 34164388.