RT Journal Article
SR Electronic
T1 BCG protects against tuberculosis irrespective of HIV status: a matched case-control study in Mwanza, Tanzania
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 288
OP 289
DO 10.1136/thoraxjnl-2012-201971
VO 68
IS 3
A1 Faurholt-Jepsen, Daniel
A1 Range, Nyagosya
A1 PrayGod, George
A1 Jeremiah, Kidola
A1 Faurholt-Jepsen, Maria
A1 Aabye, Martine G
A1 Grewal, Harleen M S
A1 Changalucha, John
A1 Witte, Daniel R
A1 Andersen, Aase B
A1 Friis, Henrik
YR 2013
UL http://thorax.bmj.com/content/68/3/288.abstract
AB While BCG vaccine protects against severe tuberculosis (TB) in children, its effect against adult TB is questionable. Furthermore, it is not known if HIV co-infection modifies the effect of BCG. Among 352 pairs of Tanzanian TB cases and matched controls, the BCG scar was associated with a reduced risk of TB (OR 0.3, 95% CI 0.2 to 0.7, p=0.005), irrespective of HIV status (interaction, p=0.623). BCG vaccination considerably reduced the risk of TB, both among individuals with and without HIV infection.