RT Journal Article
SR Electronic
T1 Virtual bronchoscopic navigation combined with endobronchial ultrasound to diagnose small peripheral pulmonary lesions: a randomised trial
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 1072
OP 1077
DO 10.1136/thx.2010.145490
VO 66
IS 12
A1 Ishida, Takashi
A1 Asano, Fumihiro
A1 Yamazaki, Koichi
A1 Shinagawa, Naofumi
A1 Oizumi, Satoshi
A1 Moriya, Hiroshi
A1 Munakata, Mitsuru
A1 Nishimura, Masaharu
A1 ,
YR 2011
UL http://thorax.bmj.com/content/66/12/1072.abstract
AB Background Bronchoscopy using endobronchial ultrasound (EBUS) can help to diagnose small peripheral pulmonary lesions. However, although biopsy sites can be confirmed, a bronchoscope cannot be guided in EBUS. Virtual bronchoscopic navigation (VBN) can guide a bronchoscope with virtual images, but its value has not been confirmed.Methods This prospective multicentre study examines the value of VBN-assisted EBUS for diagnosing small peripheral pulmonary lesions. 199 patients with small peripheral pulmonary lesions (diameter ≤30 mm) were randomly assigned to VBN-assisted (VBNA) or non-VBN-assisted (NVBNA) groups. A bronchoscope was introduced into the target bronchus of the VBNA group using the VBN system. Sites of specimen sampling were verified using EBUS with a guide sheath under fluoroscopy.Results The diagnostic yield was higher for the VBNA than for the NVBNA group (80.4% vs 67.0%; p=0.032). The duration of the examination and time elapsed until the start of sample collection were reduced in the VBNA compared with the NVBNA group (median (range), 24.0 (8.7–47.0) vs 26.2 (11.6–58.6) min, p=0.016) and 8.1 (2.8–39.2) vs 9.8 (2.3–42.3) min, p=0.045, respectively). The only adverse event was mild pneumothorax in a patient from the NVBNA group.Conclusions The diagnostic yield for small peripheral pulmonary lesions is increased when VBN is combined with EBUS.Clinical trial number UMIN000000569.