TY - JOUR T1 - The <em>sst1</em> locus controls granuloma necrosis in tuberculosis JF - Thorax JO - Thorax SP - 949 LP - 949 DO - 10.1136/thx.2009.122879 VL - 64 IS - 11 AU - M Almond Y1 - 2009/11/01 UR - http://thorax.bmj.com/content/64/11/949.abstract N2 - There is broad variation in susceptibility to Mycobacterium tuberculosis (MTB), and mouse models play a key role in elucidating the underlying mechanisms. The authors tested the hypothesis that caseation within pulmonary lesions is a specific effect of the sst1 (supersusceptibility to tuberculosis 1) locus on chromosome 1.Typical mouse lesions described in the literature lack central caseation. However, … ER -