PT  - JOURNAL ARTICLE
AU  - S Watanabe
AU  - J Tanaka
AU  - T Ohta
AU  - H Yoshizawa
AU  - F Gejyo
TI  - Paraneoplastic neurological syndrome and polyglandular autoimmune syndrome type 2 in a case of small cell lung cancer
AID  - 10.1136/thx.2007.093211
DP  - 2008 Dec 01
TA  - Thorax
PG  - 1118--1119
VI  - 63
IP  - 12
4099  - http://thorax.bmj.com/content/63/12/1118.short
4100  - http://thorax.bmj.com/content/63/12/1118.full
SO  - Thorax2008 Dec 01; 63
AB  - We report a female patient with small cell lung cancer (SCLC) and clinical findings consistent with polyglandular autoimmune syndrome type 2 (PGA2) and paraneoplastic neurological syndrome (PNS). To the best of our knowledge, this is the first reported case of SCLC associated with PGA2 and PNS. All of the autoantibodies detected before anticancer treatment decreased below the upper normal limits after serial treatment, and the patient’s clinical symptoms also improved. Cross reactivity of autoantibodies may have contributed to the complicated clinical picture of this patient.