TY - JOUR T1 - Effect of oxygen on recovery from maximal exercise in patients with chronic obstructive pulmonary disease JF - Thorax JO - Thorax SP - 668 LP - 672 DO - 10.1136/thx.2003.014209 VL - 59 IS - 8 AU - N J Stevenson AU - P M A Calverley Y1 - 2004/08/01 UR - http://thorax.bmj.com/content/59/8/668.abstract N2 - Background: The effects of oxygen on recovery from exercise in patients with chronic obstructive pulmonary disease (COPD) are not clearly known. A study was undertaken to determine whether oxygen given after maximal exercise reduced the degree of dynamic hyperinflation and so reduced the perception of breathlessness. Methods: Eighteen patients with moderate to severe COPD performed maximal symptom limited exercise on a cycle ergometer. During recovery they received either air or oxygen at identical flow rates in a randomised, single blind, crossover design. Inspiratory capacity, breathing pattern data, dyspnoea intensity, and leg fatigue scores were collected at regular intervals during recovery. At a subsequent visit patients underwent a similar protocol but with a face mask in situ to eliminate the effects of instrumentation. Results: When oxygen was given the time taken for resolution of dynamic hyperinflation was significantly shorter (mean difference between air and oxygen 6.61(1.65) minutes (95% CI 3.13 to 10.09), p = 0.001). Oxygen did not, however, reduce the perception of breathlessness during recovery nor did it affect the time taken to return to baseline dyspnoea scores in either the instrumented or non-instrumented state (mean difference 2.11 (1.41) minutes (95% CI −0.88 to 5.10), p = 0.15). Conclusions: Oxygen reduces the degree of dynamic hyperinflation during recovery from exercise but does not make patients feel less breathless than breathing air. This suggests that factors other than lung mechanics may be important during recovery from exercise, or it may reflect the cooling effect of both air and oxygen. ER -