TY - JOUR T1 - Genetic make up and environmental factors in the pathogenesis of allergic disorders JF - Thorax JO - Thorax SP - 333 LP - 333 DO - 10.1136/thx.2004.la0080 VL - 59 IS - 4 AU - A Khan Y1 - 2004/04/01 UR - http://thorax.bmj.com/content/59/4/333.abstract N2 - ▴ Gilliland FD, Li Y, Saxon A, et al. Effect of glutathione-S-transferase M1 and P1 genotype on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study. Lancet2004;363:119–25OpenUrlCrossRefPubMedWeb of Science It is well known that air pollution increases morbidity from asthma and other allergic disorders. The genetic factors that underlie this process are complex and poorly understood. Oxidative stress has emerged as an important mechanism in the toxic effects of environmental pollution. The ability of an individual to … ER -