RT Journal Article
SR Electronic
T1 Abnormal oesophageal motility in patients with chronic cough
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 699
OP 702
DO 10.1136/thorax.58.8.699
VO 58
IS 8
A1 J A Kastelik
A1 A E Redington
A1 I Aziz
A1 G K Buckton
A1 C M Smith
A1 M Dakkak
A1 A H Morice
YR 2003
UL http://thorax.bmj.com/content/58/8/699.abstract
AB Background: Although gastro-oesophageal reflux is a recognised cause of chronic cough, the role of oesophageal dysmotility is unknown. The aim of this study was to determine the prevalence of abnormal oesophageal motility in a selected group of patients with chronic cough. Methods: Oesophageal manometry and 24 hour pH monitoring were performed in 43 patients with chronic cough, 34 of whom had symptoms suggestive of gastro-oesophageal reflux. Comparative manometric measurements were made in 21 healthy subjects. Results: Nine patients with chronic cough had normal manometry and 24 hour pH. Of the remaining 34 patients, 11 (32%) had abnormal manometry alone, five (15%) had abnormal 24 hour pH monitoring alone, and in 18 (53%) both tests were abnormal. Only one patient in the control group had manometric abnormalities. Conclusions: These results point to a previously unrecognised high prevalence of abnormal oesophageal manometry in patients presenting with chronic cough. Oesophageal dysmotility may therefore be important in the pathogenesis of cough in these patients.