RT Journal Article SR Electronic T1 Chronic obstructive pulmonary disease • 5: Systemic effects of COPD JF Thorax JO Thorax FD BMJ Publishing Group Ltd and British Thoracic Society SP 1067 OP 1070 DO 10.1136/thorax.57.12.1067 VO 57 IS 12 A1 E F M Wouters YR 2002 UL http://thorax.bmj.com/content/57/12/1067.abstract AB The role of body cell mass wasting, muscle wasting, and changes in muscle metabolism in the pathogenesis of chronic obstructive pulmonary disease is reviewed.