TY - JOUR T1 - Introduction JF - Thorax JO - Thorax SP - S1 LP - S2 DO - 10.1136/thorax.55.suppl_2.S1 VL - 55 IS - suppl 2 AU - ALAN KNOX AU - ANDREW SZCZEKLIK AU - GIAMPIERO PATRIARCA Y1 - 2000/10/01 UR - http://thorax.bmj.com/content/55/suppl_2/S1.abstract N2 - There has been a considerable increase in our understanding of the role of arachidonic acid metabolites in asthma over the last decade. Arachidonic acid provides a source for both leukotrienes and prostanoids which have a diverse range of properties that are important in regulating the airway inflammatory response. It is clear that cysteinyl leukotrienes are important pro-inflammatory mediators in asthma which act to enhance bronchoconstriction. This has led to the development … ER -