RT Journal Article SR Electronic T1 Thromboembolism related to a Port-a-Cath device in a patient with cystic fibrosis. JF Thorax JO Thorax FD BMJ Publishing Group Ltd and British Thoracic Society SP 98 OP 99 DO 10.1136/thx.52.1.98 VO 52 IS 1 A1 B Yung A1 J S Elborn A1 I A Campbell A1 Y Summers A1 M Beckles A1 A A Woodcock YR 1997 UL http://thorax.bmj.com/content/52/1/98.abstract AB The case is described of a potentially life threatening complication relating to the use of a totally implantable venous access device (Port-a-Cath) in a 28 year old patient with cystic fibrosis. The device was inserted in 1990 and used repeatedly for antibiotic therapy without any complications. In 1995, during assessment for double lung transplantation, a 3 cm thrombus was found at the tip of the catheter in the right atrium. Embolisation of the thrombus to the pulmonary arteries occurred after the infusion of recombinant tissue plasminogen activator (rt-PA). Thrombus formation may be associated with totally implantable venous access devices and thromboembolism may occur following the use of thrombolytic agents in the treatment of such thrombosis.