%0 Journal Article %A M Rosenthal %A D Cramer %A S H Bain %A D Denison %A A Bush %A J O Warner %T Lung function in white children aged 4 to 19 years: II--Single breath analysis and plethysmography. %D 1993 %R 10.1136/thx.48.8.803 %J Thorax %P 803-808 %V 48 %N 8 %X OBJECTIVE--A study was performed to determine reference ranges for whole body plethysmographic gas volumes and single breath gas transfer in healthy prepubertal and pubertal schoolchildren. METHODS--The study was performed in 772 white London schoolchildren (455 male) who were clinically examined, assessed auxologically and, in 63% of cases, pubertally staged. Regression equations for the calculation of standard deviation scores were derived. RESULTS--Male lung function variables showed a discontinuous pattern of increase with standing height. Linear increases until puberty were followed by a sudden pubertal rise and a further increase with height which was more marked than before puberty. Correction for varying thoracic dimensions eliminated these changes. In females a smoother curvilinear relationship was observed with no correction possible for thoracic size. CONCLUSIONS--Male puberty leads to profound changes in pulmonary function mostly related to thoracic size, an effect not observed in females. %U https://thorax.bmj.com/content/thoraxjnl/48/8/803.full.pdf