@article {Rosenthal803, author = {M Rosenthal and D Cramer and S H Bain and D Denison and A Bush and J O Warner}, title = {Lung function in white children aged 4 to 19 years: II--Single breath analysis and plethysmography.}, volume = {48}, number = {8}, pages = {803--808}, year = {1993}, doi = {10.1136/thx.48.8.803}, publisher = {BMJ Publishing Group Ltd}, abstract = {OBJECTIVE--A study was performed to determine reference ranges for whole body plethysmographic gas volumes and single breath gas transfer in healthy prepubertal and pubertal schoolchildren. METHODS--The study was performed in 772 white London schoolchildren (455 male) who were clinically examined, assessed auxologically and, in 63\% of cases, pubertally staged. Regression equations for the calculation of standard deviation scores were derived. RESULTS--Male lung function variables showed a discontinuous pattern of increase with standing height. Linear increases until puberty were followed by a sudden pubertal rise and a further increase with height which was more marked than before puberty. Correction for varying thoracic dimensions eliminated these changes. In females a smoother curvilinear relationship was observed with no correction possible for thoracic size. CONCLUSIONS--Male puberty leads to profound changes in pulmonary function mostly related to thoracic size, an effect not observed in females.}, issn = {0040-6376}, URL = {https://thorax.bmj.com/content/48/8/803}, eprint = {https://thorax.bmj.com/content/48/8/803.full.pdf}, journal = {Thorax} }