PT  - JOURNAL ARTICLE
AU  - Campbell, J H
AU  - Winter, J H
AU  - Richardson, M D
AU  - Shankland, G S
AU  - Banham, S W
TI  - Treatment of pulmonary aspergilloma with itraconazole.
AID  - 10.1136/thx.46.11.839
DP  - 1991 Nov 01
TA  - Thorax
PG  - 839--841
VI  - 46
IP  - 11
4099  - http://thorax.bmj.com/content/46/11/839.short
4100  - http://thorax.bmj.com/content/46/11/839.full
SO  - Thorax1991 Nov 01; 46
AB  - In a 12 month open study of itraconazole in pulmonary aspergilloma nine patients received oral itraconazole 200 mg daily for six months followed by further itraconazole or observation for a further six months. There was no change in the serum IgG specific for Aspergillus fumigatus (mean (SE) change -4% (10%)) or symptoms of chronic cough and haemoptysis. In two of the three patients who continued treatment beyond six months symptoms and radiographic appearances improved and a temporary reduction in A fumigatus specific IgG occurred in one patient. Further experience of the effects of longer treatment are needed before oral itraconazole can be recommended for aspergilloma.