TY - JOUR T1 - Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects. JF - Thorax JO - Thorax SP - 500 LP - 504 DO - 10.1136/thx.39.7.500 VL - 39 IS - 7 AU - N C Barnes AU - P J Piper AU - J F Costello Y1 - 1984/07/01 UR - http://thorax.bmj.com/content/39/7/500.abstract N2 - The comparative actions of inhaled leukotriene C4 (LTC4), leukotriene D4 (LTD4), and histamine were studied in six normal subjects. LTC4 and LTD4 were shown to be more potent bronchoconstrictors than histamine, with a more sustained action. LTC4 and LTD4 caused wheezing without cough or throat irritation and were shown to act on large and small airways. ER -