PT - JOURNAL ARTICLE AU - N C Barnes AU - P J Piper AU - J F Costello TI - Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects. AID - 10.1136/thx.39.7.500 DP - 1984 Jul 01 TA - Thorax PG - 500--504 VI - 39 IP - 7 4099 - http://thorax.bmj.com/content/39/7/500.short 4100 - http://thorax.bmj.com/content/39/7/500.full SO - Thorax1984 Jul 01; 39 AB - The comparative actions of inhaled leukotriene C4 (LTC4), leukotriene D4 (LTD4), and histamine were studied in six normal subjects. LTC4 and LTD4 were shown to be more potent bronchoconstrictors than histamine, with a more sustained action. LTC4 and LTD4 caused wheezing without cough or throat irritation and were shown to act on large and small airways.