RT Journal Article
SR Electronic
T1 Running, walking, and hyperventilation causing asthma in children.
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 582
OP 586
DO 10.1136/thx.34.5.582
VO 34
IS 5
A1 H Kilham
A1 M Tooley
A1 M Silverman
YR 1979
UL http://thorax.bmj.com/content/34/5/582.abstract
AB To examine further the relation between type of exercise, workload, ventilation, and exercise-induced asthma, we compared treadmill walking with treadmill running and treadmill running with isocapnic hyperventilation in separate studies in children and adolescents. Inspired air conditions were identical during each pair of tests. Walking and running with similar minute ventilation and oxygen consumption were followed by similar falls in peak expiratory flow rate as were running and hyperventilation with similar minute ventilation and end-tidal carbon dioxide tension. This study supports the concept that hyperventilation is a central mechanism in exercise-induced asthma.