RT Journal Article
SR Electronic
T1 Pulmonary involvement in primary biliary cirrhosis.
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 208
OP 212
DO 10.1136/thx.36.3.208
VO 36
IS 3
A1 R Rodriguez-Roisin
A1 A Pares
A1 M Bruguera
A1 J Coll
A1 C Picado
A1 A Agusti-Vidal
A1 F Burgos
A1 J Rodes
YR 1981
UL http://thorax.bmj.com/content/36/3/208.abstract
AB The association of pulmonary fibrosis and primary biliary cirrhosis (PBC) remains controversial. To determine the frequency of pulmonary fibrosis in PBC, a carefully selected series of 14 PBC patients, seven patients with Sicca complex, and 14 control subjects have been studied. Seven of the 14 patients with PBC had Sjögren's syndrome, four of whom had some clinical evidence of pulmonary disease. Evaluation of ventilatory capacity, gas transfer factor, arterial blood gases, and lung mechanics were performed. Gas transfer was reduced in patients with PBC associated with Sjögen's syndrome and in patients with the Sicca complex. These results suggest that the respiratory, clinical, ad functional abnormalities found in PBC are related to the presence of an associated Sjögen's syndrome.