RT Journal Article
SR Electronic
T1 A double-blind cross-over trial of trimethoprim and sulphamethoxazole in chronic bronchitis
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 319
OP 324
DO 10.1136/thx.26.3.319
VO 26
IS 3
A1 Ian W. Webster
YR 1971
UL http://thorax.bmj.com/content/26/3/319.abstract
AB A double-blind cross-over trial comparing trimethoprim-sulphamethoxazole with sulphamethoxazole in patients with chronic bronchitis in their usual state of health showed that the combination was more effective in reducing the volume and purulence of the sputum. Although the patients preferred treatment with the combination, there was no objective improvement in respiratory function. There was a significant incidence of side effects.