RT Journal Article
SR Electronic
T1 Pores of Kohn
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP 433
OP 441
DO 10.1136/thx.27.4.433
VO 27
IS 4
A1 J. L. Cordingley
YR 1972
UL http://thorax.bmj.com/content/27/4/433.abstract
AB The history of the investigations into interalveolar communications (pores of Kohn) shows that the question whether they exist and, if so, their nature has for approximately a century been contentious. The present electron microscopic study of the lungs of mice demonstrates that alveolar pores are normal structures, with edges composed of intact alveolar wall. A number of planes are demonstrated from which a fully compatible reconstruction is made. It is concluded that pores are round or oval structures frequently having at least one type II alveolar cell forming part of their boundary. It is further postulated that pores may be divided by a capillary column stretching across the space, resulting in two openings. A type II alveolar cell forming part of the pore wall may straddle the capillary column. Alveolar macrophages may be found lying free in the pore or lying astride a capillary column. When lying in a corner position type II cells may occupy the full wall thickness and face into three alveoli.