%0 Journal Article %A Pierre P. Tulou %T Cardiac output and arterial CO2 response during intermittent positive pressure breathing with oxygen %B A comparison of patients with chronic airflow obstruction and controls %D 1971 %R 10.1136/thx.26.1.33 %J Thorax %P 33-38 %V 26 %N 1 %X Cardiac output and arterial blood gases were studied before, during, and after intermittent positive pressure breathing, using 40% oxygen (IPPB/O2). The subjects of this study were eight patients with lung disease, seven of them with chronic airflow obstruction and eight control subjects without respiratory symptoms. During IPPB/O2, cardiac output was definitely lowered without a significant decrease in arterial Pco2 in the patients with airflow obstruction. Conversely, the control subjects during IPPB/O2 had a large decrease in arterial Pco2 with a moderate reduction in cardiac output. Considering this response of the lung with airflow obstruction, the more frequent use of cardiac output and arterial gas measurements in patients receiving IPPB/O2 treatments appears desirable. Individual cases are presented. %U https://thorax.bmj.com/content/thoraxjnl/26/1/33.full.pdf