eLetters

178 e-Letters

published between 2003 and 2006

  • The effectiveness of a multidisciplinary approach in the management of lung cancer
    Prashant S Borade

    Dear Editor,

    Lung cancer accounts for 1 in 3 cancer deaths and 25% of cancer registrations. Recognition that accurate and prompt diagnosis can help save lives has led to the formation of the multidisciplinary team (MDT), which consists primarily of chest physicians, thoracic surgeons, radiologists, pathologists, and oncologists, in the management of patients with lung cancer.

    A study was conducted to assess the...

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  • Anti-inflammatory effects of modern histamine H1-receptor antagonists in atopic asthma
    Daniel K C Lee

    Dear Editor,

    Controversy exists as to the role of modern histamine H1-receptor antagonists in the treatment of atopic asthma.

    Forty-nine patients with atopic asthma were evaluated from three randomised double-blind placebo-controlled cross-over studies assessing the anti-inflammatory effects of desloratadine, fexofenadine, and levocetirizine at clinically recommended doses.

    Desloratadine, fexo...

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  • Normal range of exhaled breath condensate pH
    Zoe L Borrill

    Dear Editor,

    We read with interest the recent paper by Ojoo et al. [1] showing dissociation between exhaled breath condensate (EBC) pH and FENO in patients with asthma and cystic fibrosis. We note that EBC pH was measured without prior deaeration of the sample using argon gas, in common with other studies [2,3]. An alternative method is to pass argon gas through or over EBC samples in order to remove dissolved c...

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  • Long Term Health Benefits
    Leonie R Rauputu

    Dear Editor,

    I am a Respiratory Nurse Educator working daily with Maori Clients in the Waikato, in regards to smoking cessation, and so it was with great interest that I read the article 'Efficacy of bupropion in the indigenous Maori population in New Zealand'. (Thorax 2005:60:120-123).

    While it is encouraging to see the success rate in the study group, it is very disappointing to see so many lost to fol...

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  • RBILD or DIP? That is the question
    Ritesh Agarwal

    Dear Editor,

    We read with interest the case report “Respiratory bronchiolitis associated interstitial lung disease (RB-ILD): a case of an acute presentation” published in Thorax 2004; 59: 910–911. The case presented was of a young female, a heavy smoker, diagnosed as acute interstitial lung disease (ILD) based on clinical presentation, and respiratory bronchiolitis associated interstitial lung disease (RBILD) o...

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  • Authors' Response
    Don D. Sin

    Dear Editor

    The authors wish to thank Fimognari and colleagues for highlighting the difficult issue of defining chronic obstructive pulmonary disease (COPD). In most circumstances, a spirometric cutoff is used to define COPD, but there is no uniform consensus on what that should be and different expert panels have promulgated different spirometric cutoff values [1-4]. COPD is a disease characterized by lung inflam...

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  • Permissive Hypoxemia in ARDS – Is There a Place for a New Strategy?
    Mohamad Abdelsalam Abdelkader

    Dear Editor

    The acute respiratory distress syndrome (ARDS) was first described in 1967, when Ashbaugh and colleagues reported 12 patients with acute respiratory distress, cyanosis refractory to oxygen therapy, decreased lung compliance and diffuse pulmonary infiltrates on the chest radiograph (1). In 1994, new definition was recommended by the American-European Consensus Conference that has been widely accepted by...

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  • The Cutting Edge
    Calvin S.H. Ng

    Dear Editor

    “A good surgeon knows how to operate. A better surgeon knows when to operate. The best surgeon knows when not to operate.”

    Clinical Surgery in General 3rd Edition Royal College of Surgeons of England Course Manual

    We found the article "Effect of comorbidity on the treatment and prognosis of elderly patients with non-small cell lung cancer" by Janssen- Heijnen et al [1] very interesti...

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  • Tuberculosis screening and anti-TNF-alpha therapy
    Giuseppe Provenzano

    Dear Editor

    Reactivation of tuberculosis (TB) is a major concern during treatment with TNF inhibitors [1]. Different guidelines to detect active and latent TB have been reccomended in various countries before starting therapy with these drugs. There is evidence that their application has led to a significant reduction in the number of cases of TB [2], but we do not know which is the most cost-effective strategy. At...

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  • Primary spontaneous pneumothorax: evidence-based revision of management guidelines
    Stewart Siu-Wa Chan

    Dear Editor

    The British Thoracic Society (BTS) guidelines for the management of primary spontaneous pneumothorax (PSP) recommend simple aspiration as the first line treatment for all cases of PSP requiring intervention.[1] However, studies in the UK have shown that compliance is poor, and that simple aspiration is under-utilised.[2,3] Henry et al suggested that poor compliance may be due to an unwillingness to...

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