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Chronic obstructive pulmonary disease
Original research
Th2 high and mast cell gene signatures are associated with corticosteroid sensitivity in COPD

Authors

  • Alen Faiz Respiratory Bioinformatics and Molecular Biology, University of Technology Sydney, Ultimo, New South Wales, AustraliaPulmonary Diseases, UMCG, Groningen, The NetherlandsGRAIC, University of Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Stelios Pavlidis Department of Computing and Data Science Institute, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Chih-Hsi Kuo Department of Computing and Data Science Institute, Imperial College London, London, UKAirways Disease, Respiratory Cell & Molecular Biology, Airways Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Anthony Rowe Discovery IT, Janssen Research and Development LLC, High Wycombe, UK PubMed articlesGoogle scholar articles
  • Pieter S Hiemstra Pulmonology, Leiden University Medical Center, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Wim Timens GRAIC, University of Groningen, Groningen, The NetherlandsPathology and Medical Biology, University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Marijn Berg GRAIC, University of Groningen, Groningen, The NetherlandsPathology and Medical Biology, University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Marissa Wisman GRAIC, University of Groningen, Groningen, The NetherlandsPathology and Medical Biology, University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Yi-Ke Guo Department of Computing and Data Science Institute, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Ratko Djukanović Academic Unit of Clinical and Experimental Sciences, Southampton University Faculty of Medicine, Southampton, UK PubMed articlesGoogle scholar articles
  • Peter Sterk Respiratory Medicine, Amsterdam UMC—Locatie AMC, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Kerstin B Meyer Gene expression genomics, Wellcome Sanger Institute, Hinxton, UK PubMed articlesGoogle scholar articles
  • Martijn C Nawijn GRAIC, University of Groningen, Groningen, The NetherlandsPathology and Medical Biology, University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Ian Adcock Department of Computing and Data Science Institute, Imperial College London, London, UKAirways Disease, Respiratory Cell & Molecular Biology, Airways Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Kian Fan Chung Department of Computing and Data Science Institute, Imperial College London, London, UKAirways Disease, Respiratory Cell & Molecular Biology, Airways Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Maarten van den Berge Pulmonary Diseases, UMCG, Groningen, The NetherlandsGRAIC, University of Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Alen Faiz, Respiratory Bioinformatics and Molecular Biology, University of Technology Sydney, Ultimo, New South Wales 2007, Australia; Alen.Faiz{at}uts.edu.au
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Citation

Faiz A, Pavlidis S, Kuo C, et al
Th2 high and mast cell gene signatures are associated with corticosteroid sensitivity in COPD
Thorax 2023;78:335-343.

Publication history

  • Received July 6, 2021
  • Accepted October 27, 2022
  • First published December 7, 2022.
Online issue publication 
May 16, 2023

  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

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Copyright information

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.