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Circulating microbial cell-free DNA is associated with inflammatory host-responses in severe pneumonia

Authors

  • Haopu Yang School of Medicine, Tsinghua University, Beijing, People's Republic of ChinaDepartment of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USADivision of Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USACenter for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Ghady Haidar Division of Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Nameer S Al-Yousif Internal Medicine Residency Program, Mercy, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Haris Zia Internal Medicine Residency Program, McKeesport, University of Pittsburgh Medical Center, McKeesport, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Daniel Kotok Weston Hospital, Cleveland Clinic Florida, Weston, Florida, USA PubMed articlesGoogle scholar articles
  • Asim A Ahmed Karius Inc, Redwood City, California, USA PubMed articlesGoogle scholar articles
  • Lily Blair Karius Inc, Redwood City, California, USA PubMed articlesGoogle scholar articles
  • Sudeb Dalai Karius Inc, Redwood City, California, USA PubMed articlesGoogle scholar articles
  • Sivan Bercovici Karius Inc, Redwood City, California, USA PubMed articlesGoogle scholar articles
  • Carine Ho Karius Inc, Redwood City, California, USA PubMed articlesGoogle scholar articles
  • Bryan J McVerry Division of Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USACenter for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USAAcute Lung Injury Center for Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Alison Morris Division of Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USACenter for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USAAcute Lung Injury Center for Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania, USADepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Georgios D Kitsios Division of Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USACenter for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USAAcute Lung Injury Center for Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Georgios D Kitsios, Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh Medical Center Health System, Pittsburgh, PA 15213, USA; kitsiosg{at}upmc.edu
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Citation

Yang H, Haidar G, Al-Yousif NS, et al
Circulating microbial cell-free DNA is associated with inflammatory host-responses in severe pneumonia

Publication history

  • Received August 15, 2020
  • Revised March 7, 2021
  • Accepted March 21, 2021
  • First published April 22, 2021.

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