Change in type-2 biomarkers and related cytokines with prednisolone in uncontrolled severe oral corticosteroid dependent asthmatics: an interventional open-label study

John Busby; Cecile T J Holweg; Akiko Chai; Peter Bradding; Fang Cai; Rekha Chaudhuri; Adel H Mansur; James Laurence Lordan; John G Matthews; Andrew Menzies-Gow; Robert Niven; Tracy Staton; Liam G Heaney

doi:10.1136/thoraxjnl-2018-212709

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Change in type-2 biomarkers and related cytokines with prednisolone in uncontrolled severe oral corticosteroid dependent asthmatics: an interventional open-label study

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John Busby Centre for Experimental Medicine, Queen's University Belfast School of Medicine Dentistry and Biomedical Sciences, Belfast, UK PubMed articles Google scholar articles
Cecile T J Holweg Genentech Inc. (a member of the Roche Group), South San Francisco, California, USA PubMed articles Google scholar articles
Akiko Chai Genentech Inc. (a member of the Roche Group), South San Francisco, California, USA PubMed articles Google scholar articles
Peter Bradding Institute for Lung Health, Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK PubMed articles Google scholar articles
Fang Cai Genentech Inc. (a member of the Roche Group), South San Francisco, California, USA PubMed articles Google scholar articles
Rekha Chaudhuri Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, Scotland PubMed articles Google scholar articles
Adel H Mansur Respiratory, Heartlands Hospital, Birmingham, UK PubMed articles Google scholar articles
James Laurence Lordan Respiratory, Freeman Hospital, Newcastle upon Tyne, UK PubMed articles Google scholar articles
John G Matthews Product Development, Genentech Inc. (a member of the Roche Group), South San Francisco, California, USA PubMed articles Google scholar articles
Andrew Menzies-Gow Royal Brompton Hospital, London, UK PubMed articles Google scholar articles
Robert Niven Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK PubMed articles Google scholar articles
Tracy Staton Genentech Inc. (a member of the Roche Group), South San Francisco, California, USA PubMed articles Google scholar articles
Liam G Heaney Centre of Infection and Immunity, Queens University Belfast, Belfast, UK PubMed articles Google scholar articles

Correspondence to Professor Liam G Heaney, Centre for Experimental Medicine, Queens University Belfast, Belfast BT9 7BL, UK; l.heaney{at}qub.ac.uk

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Busby J, Holweg CTJ, Chai A, et al

Change in type-2 biomarkers and related cytokines with prednisolone in uncontrolled severe oral corticosteroid dependent asthmatics: an interventional open-label study

Thorax 2019;74:806-809.

Publication history

Received October 10, 2018
Revised January 7, 2019
Accepted February 25, 2019
First published April 2, 2019.

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February 07, 2024

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