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  • A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis

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Chest clinic
Audit, research and guideline update
A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis
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Authors

  • Eric W F W Alton UK CF Gene Therapy Consortium, Edinburgh, London, Oxford, UK Department of Gene Therapy, Imperial College London, London, UK Department of Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • A Christopher Boyd UK CF Gene Therapy Consortium, Edinburgh, London, Oxford, UK Medical Genetics Section, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Seng H Cheng Department of Rare Diseases Science, Genzyme, a Sanofi Company, Framingham, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Steve Cunningham UK CF Gene Therapy Consortium, Edinburgh, London, Oxford, UK Department of Respiratory and Sleep Medicine, Royal Hospital for Sick Children, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Jane C Davies UK CF Gene Therapy Consortium, Edinburgh, London, Oxford, UK Department of Gene Therapy, Imperial College London, London, UK Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • Deborah R Gill UK CF Gene Therapy Consortium, Edinburgh, London, Oxford, UK Gene Medicine Group, Nuffield Division of Clinical Laboratory Sciences, University of Oxford, Oxford, UK PubMed articlesGoogle scholar articles
  • Uta Griesenbach UK CF Gene Therapy Consortium, Edinburgh, London, Oxford, UK Department of Gene Therapy, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Tracy Higgins UK CF Gene Therapy Consortium, Edinburgh, London, Oxford, UK Department of Gene Therapy, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Stephen C Hyde UK CF Gene Therapy Consortium, Edinburgh, London, Oxford, UK Gene Medicine Group, Nuffield Division of Clinical Laboratory Sciences, University of Oxford, Oxford, UK PubMed articlesGoogle scholar articles
  • J Alastair Innes UK CF Gene Therapy Consortium, Edinburgh, London, Oxford, UK Medical Genetics Section, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Gordon D Murray Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • David J Porteous UK CF Gene Therapy Consortium, Edinburgh, London, Oxford, UK Medical Genetics Section, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Jane C Davies, Department of Gene Therapy, National Heart and Lung Institute, Imperial College, Emmanuel Kaye Building, 1b Manresa Road, London SW3 6LR, UK; j.c.davies{at}imperial.ac.uk
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Citation

Alton EWFW, Boyd AC, Cheng SH, et al
A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis
Thorax 2013;68:1075-1077.

Publication history

  • Received January 24, 2013
  • Revised February 21, 2013
  • Accepted February 25, 2013
  • First published March 22, 2013.
Online issue publication 
September 01, 2022

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