You are here

Article Text

Article menu

other Versions

Download PDFPDF
Miscellanea
Journal club
Human neutrophil chemotaxis regulation by α-1 antitrypsin
  1. L H White
  1. Correspondence to L H White, Respiratory Department, Great Western Hospital, Swindon, UK; laura.white{at}gwh.nhs.uk

https://doi.org/10.1136/thoraxjnl-2011-200116

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    α-1 Antitrypsin (AAT) has anti-inflammatory roles beyond regulation of proteases. Chronic lung disease in α-1 antitrypsin deficiency (AATD) is characterised by neutrophilic inflammation. This series of experiments investigated the effects of AAT on neutrophil chemotaxis by comparing neutrophils from patients with AATD with controls, both in vitro and in vivo.

    Chemotaxis to both IL-8 and soluble …

    View Full Text