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Genetic variants and risk of lung cancer in never smokers
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This four-stage study systematically investigated common genetic variations associated with the risk of developing lung cancer in never smokers. Stage 1 involved a genome-wide association study at the Mayo Clinic. A total of 331 918 single nucleotide polymorphisms (SNPs) in 377 case–control matched pairs were analysed. The 44 most significant SNPs that might alter the risk of …