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Lung alert
Genetic variants and risk of lung cancer in never smokers
  1. Abbey Leahy
  1. Correspondence to Abbey Leahy, Respiratory SpR, United Bristol Hospital NHS Foundation Trust, Bristol BS1 3NU, UK; abbey.leahy{at}UHBristol.nhs.uk

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This four-stage study systematically investigated common genetic variations associated with the risk of developing lung cancer in never smokers. Stage 1 involved a genome-wide association study at the Mayo Clinic. A total of 331 918 single nucleotide polymorphisms (SNPs) in 377 case–control matched pairs were analysed. The 44 most significant SNPs that might alter the risk of …

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