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Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD
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  1. Dr Diana C Grootendorst, Department of Pulmonology C3-P, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands; d.c.Grootendorst{at}lumc.nl
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Grootendorst DC, Gauw SA, Verhoosel RM, et al
Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD

Publication history

  • Received December 1, 2006
  • Accepted May 16, 2007
  • First published June 15, 2007.
Online issue publication 
September 01, 2022

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