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  • Symptom-related screening programme for early detection of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: the SYSPPE study

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Pulmonary vasculature
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Symptom-related screening programme for early detection of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: the SYSPPE study
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  • Published on: 7 February 2024
    Baseline post-PE assessment

    Thank you to the authors for the excellent and very interesting work published.

    I would like to ask about the protocol routine follow-up of patients following an acute pulmonary embolus mentioned in the paper: what did this entail, and how did it differ from the protocol implemented as part of the trial?

    Secondly, how did the authors select a follow-up telephone at 2 years post acute pulmonary embolus? As is pointed out in the limitations of section of the paper, this could have missed patients with clinically significant CTEPH who did not survive those 2 years. Would an earlier symptom assessment have led to a greater incidence of false positive echocardiograms showing pulmonary hypertension, or would it lead to patients being missed as not enough time would have passed to allow CTEPH to establish?

    Thank you in advance for your clarifications

    Conflict of Interest:
    None declared.