Original research
Long-term effect of pulmonary rehabilitation in idiopathic pulmonary fibrosis: a randomised controlled trial
Compose Response

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g.
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Statement of Competing Interests


  • A rapid response is a moderated but not peer reviewed online response to a published article in a BMJ journal; it will not receive a DOI and will not be indexed unless it is also republished as a Letter, Correspondence or as other content. Find out more about rapid responses.
  • We intend to post all responses which are approved by the Editor, within 14 days (BMJ Journals) or 24 hours (The BMJ), however timeframes cannot be guaranteed. Responses must comply with our requirements and should contribute substantially to the topic, but it is at our absolute discretion whether we publish a response, and we reserve the right to edit or remove responses before and after publication and also republish some or all in other BMJ publications, including third party local editions in other countries and languages
  • Our requirements are stated in our rapid response terms and conditions and must be read. These include ensuring that: i) you do not include any illustrative content including tables and graphs, ii) you do not include any information that includes specifics about any patients,iii) you do not include any original data, unless it has already been published in a peer reviewed journal and you have included a reference, iv) your response is lawful, not defamatory, original and accurate, v) you declare any competing interests, vi) you understand that your name and other personal details set out in our rapid response terms and conditions will be published with any responses we publish and vii) you understand that once a response is published, we may continue to publish your response and/or edit or remove it in the future.
  • By submitting this rapid response you are agreeing to our terms and conditions for rapid responses and understand that your personal data will be processed in accordance with those terms and our privacy notice.
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

Other responses

  • Published on:
    Potential benefits of long-term pulmonary rehabilitation to preserve exercise capacity in patients with idiopathic pulmonary fibrosis treated with antifibrotic drugs.
    • Kazuki Okura, Physiotherapist Division of Rehabilitation, Akita University Hospital
    • Other Contributors:
      • Masahiro Iwakura, Physiotherapist

    We were interested in the article "Long-term effect of pulmonary rehabilitation in idiopathic pulmonary fibrosis: a randomised controlled trial" by Kataoka K. et al. [1] The effect of pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis (IPF) is a topical theme in this field. We believe that this multicenter randomised controlled trial conducted in Japan will have an enormous impact on the knowledge of pulmonary rehabilitation in patients with IPF.
    The authors conducted a 12-week supervised and home-based unsupervised exercise therapy-based pulmonary rehabilitation for 45 outpatients with IPF treated with antifibrotic drugs. In addition, the patients were followed by a 40-week home-based unsupervised exercise therapy-based maintenance program. The pulmonary rehabilitation resulted in a more significant change (week 52 - Baseline) in endurance time measured by a constant workload test using a bicycle ergometer compared to 43 control patients who received only usual care (mean difference: 187 s [95% CI: 34 to 153]). Although endurance time is a secondary outcome in the authors' study design, this result suggests that IPF patients treated with antifibrotic drugs may benefit from pulmonary rehabilitation as a combination therapy to maintain exercise tolerance.
    In contrast, the authors found no statistically significant between-group differences in the change in 6-minute walking distance (6MWD) (52 weeks - Baseline), the prima...

    Show More
    Conflict of Interest:
    None declared.