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Case-based discussion: neonates on extracorporeal membrane oxygenation for undiagnosed recalcitrant pulmonary hypertension—management challenges
  1. John A King1,2,
  2. Ajay Desai3,
  3. Tom Semple4,
  4. Andrew G Nicholson5,
  5. Andrew Bush1,2,
  6. Samatha Sonnappa1,2
  1. 1 Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
  2. 2 National Heart and Lung Institute, Imperial College London, London, UK
  3. 3 Royal Brompton Hospital, London, UK
  4. 4 Radiology, Royal Brompton Hospital, London, UK
  5. 5 Department of Histopathology, Royal Brompton Hospital, London, UK
  1. Correspondence to Dr Samatha Sonnappa, Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK; s.sonnappa{at}rbht.nhs.uk

Abstract

We present two neonates requiring extracorporeal membrane oxygenation for undiagnosed recalcitrant pulmonary hypertension, highlighting the clinical and ethical dilemmas in management of very rare diseases.

  • paediatric interstitial lung disease
  • paediatric lung disaese

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Footnotes

  • Contributors JAK wrote the case summaries, reviewed relevant literature and drafted the case discussion. AGN and TS provided histology and radiology descriptions, respectively. AD, AB and SS edited the discussion and agreed learning points. Informed, written consent was obtained from the parents of children presented in these cases.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.