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  • Inhaled gene therapy of preclinical muco-obstructive lung diseases by nanoparticles capable of breaching the airway mucus barrier

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Respiratory research
Original research
Inhaled gene therapy of preclinical muco-obstructive lung diseases by nanoparticles capable of breaching the airway mucus barrier

Authors

  • Namho Kim Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins Medicine, Baltimore, Maryland, USA Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Whiting School of Engineering, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Gijung Kwak Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins Medicine, Baltimore, Maryland, USA Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Jason Rodriguez Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins Medicine, Baltimore, Maryland, USA Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Alessandra Livraghi-Butrico Marisco Lung Institute and Cystic Fibrosis Research Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Xinyuan Zuo Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Whiting School of Engineering, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Valentina Simon Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Eric Han Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Siddharth Kaup Shenoy Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins Medicine, Baltimore, Maryland, USA Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Nikhil Pandey Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Marina Mazur Gregory Fleming James Cystic Fibrosis Research Center, The University of Alabama School of Medicine, Birmingham, Alabama, USA PubMed articlesGoogle scholar articles
  • Susan E Birket Gregory Fleming James Cystic Fibrosis Research Center, The University of Alabama School of Medicine, Birmingham, Alabama, USA Department of Medicine, The University of Alabama, Birmingham, Alabama, USA PubMed articlesGoogle scholar articles
  • Anthony Kim Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Steven M Rowe Gregory Fleming James Cystic Fibrosis Research Center, The University of Alabama School of Medicine, Birmingham, Alabama, USA Department of Medicine, The University of Alabama, Birmingham, Alabama, USA PubMed articlesGoogle scholar articles
  • Richard Boucher Marisco Lung Institute and Cystic Fibrosis Research Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Justin Hanes Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins Medicine, Baltimore, Maryland, USA Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Whiting School of Engineering, Baltimore, Maryland, USA Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA Department of Biomedical Engineering, Environmental and Health Sciences, Oncology, Neurosurgery, and Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Jung Soo Suk Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins Medicine, Baltimore, Maryland, USA Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Whiting School of Engineering, Baltimore, Maryland, USA Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Jung Soo Suk, Center for Nanomedicine, Johns Hopkins Medicine Wilmer Eye Institute, Baltimore, Maryland, USA; jsuk{at}jhmi.edu
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Citation

Kim N, Kwak G, Rodriguez J, et al
Inhaled gene therapy of preclinical muco-obstructive lung diseases by nanoparticles capable of breaching the airway mucus barrier
Thorax 2022;77:812-820.

Publication history

  • Received June 4, 2020
  • Accepted August 27, 2021
  • First published October 25, 2021.
Online issue publication 
July 25, 2022

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© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.