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Periodic breathing during hypoxia altitude simulation test
  1. Santiago C. Arce1,
  2. Guillermo B. Semeniuk1,
  3. Eduardo L. De Vito1,2
  1. 1 Pulmonary Function Laboratory, Instituto de Investigaciones Médicas Dr. Alfredo Lanari, Buenos Aires, Argentina
  2. 2 Centro del Parque, Buenos Aires, Argentina
  1. Correspondence to Dr. Santiago C. Arce, Instituto de Investigaciones Médicas Dr. Alfredo Lanari, Buenos Aires, Argentina; arcesantiago{at}

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A 79-year-old slender female patient presented at the pulmonary function laboratory to perform a hypoxia altitude simulation test (HAST). It was indicated on the basis of her intention to travel by plane and a diagnosis of idiopathic pulmonary fibrosis (IPF). She was a former smoker and had a history of arterial hypertension. Her only symptoms were mMRC grade 2 dyspnoea and cough.

The test was performed at sea level through a tightly fitting facemask, attached to a pneumotachograph and a two-way non-rebreathing valve. Dead space of the circuit was 120 mL. Airflow, heart rate, inspired oxygen and carbon dioxide fraction were continuously recorded. Pulse oximetry (SpO2) was recorded trough a finger probe (Massimo Radical 7, California, USA). In the sitting position, the patient breathed ambient air (inspired oxygen percentage=21%) …

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  • Contributors SCA performed the test, analysed the results and wrote the draft; GBS collected clinical data and followed up the patient; ELDV supervised and revised the final draft.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.