Effect of CRTH2 antagonism on the response to experimental rhinovirus infection in asthma: a pilot randomised controlled trial

Hugo Farne; Nicholas Glanville; Nicholas Johnson; Tata Kebadze; Julia Aniscenko; Eteri Regis; Jie Zhu; Maria-Belen Trujillo-Torralbo; Onn Min Kon; Patrick Mallia; A Toby Prevost; Michael R Edwards; Sebastian L Johnston; Aran Singanayagam; David J Jackson

doi:10.1136/thoraxjnl-2021-217429

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Asthma

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Effect of CRTH2 antagonism on the response to experimental rhinovirus infection in asthma: a pilot randomised controlled trial

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Hugo Farne National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Nicholas Glanville National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Nicholas Johnson Imperial Clinical Trials Unit, Imperial College London, London, UK PubMed articles Google scholar articles
Tata Kebadze National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Julia Aniscenko National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Eteri Regis National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Jie Zhu National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Maria-Belen Trujillo-Torralbo National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Onn Min Kon National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Patrick Mallia National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
A Toby Prevost Imperial Clinical Trials Unit, Imperial College London, London, UK PubMed articles Google scholar articles
Michael R Edwards National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Sebastian L Johnston National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Aran Singanayagam National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
David J Jackson Guy’s Severe Asthma Centre, Guy’s and St Thomas’ NHS Foundation Trust, London, UK MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King’s College London, London, UK PubMed articles Google scholar articles

Correspondence to Professor Sebastian L Johnston, National Heart and Lung Institute, Imperial College London, London, UK; s.johnston{at}imperial.ac.uk

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Farne H, Glanville N, Johnson N, et al

Effect of CRTH2 antagonism on the response to experimental rhinovirus infection in asthma: a pilot randomised controlled trial

Thorax 2022;77:950-959.

Publication history

Received April 9, 2021
Accepted September 24, 2021
First published October 29, 2021.

Online issue publication

March 28, 2024

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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