Latent class analysis-derived subphenotypes are generalisable to observational cohorts of acute respiratory distress syndrome: a prospective study

Pratik Sinha; Kevin L Delucchi; Yue Chen; Hanjing Zhuo; Jason Abbott; Chunxue Wang; Nancy Wickersham; J Brennan McNeil; Alejandra Jauregui; Serena Ke; Kathryn Vessel; Antonio Gomez; Carolyn M Hendrickson; Kirsten N Kangelaris; Aartik Sarma; Aleksandra Leligdowicz; Kathleen D Liu; Michael A Matthay; Lorraine B Ware; Carolyn S Calfee

doi:10.1136/thoraxjnl-2021-217158

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Latent class analysis-derived subphenotypes are generalisable to observational cohorts of acute respiratory distress syndrome: a prospective study

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Pratik Sinha Department of Anesthesiology, Washington University in St Louis, St Louis, Missouri, USA PubMed articles Google scholar articles
Kevin L Delucchi Department of Psychiatry, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Yue Chen Department of Medicine, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Hanjing Zhuo Department of Anesthesiology, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Jason Abbott Department of Anesthesiology, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Chunxue Wang Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA PubMed articles Google scholar articles
Nancy Wickersham Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA PubMed articles Google scholar articles
J Brennan McNeil Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA PubMed articles Google scholar articles
Alejandra Jauregui Department of Medicine, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Serena Ke Department of Medicine, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Kathryn Vessel Department of Medicine, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Antonio Gomez Department of Medicine, University of California San Francisco, San Francisco, California, USA Department of Medicine, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California, USA PubMed articles Google scholar articles
Carolyn M Hendrickson Department of Medicine, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California, USA PubMed articles Google scholar articles
Kirsten N Kangelaris Department of Medicine, University of California San Francisco, San Francisco, California, USA University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Aartik Sarma Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, California, USA PubMed articles Google scholar articles
Aleksandra Leligdowicz Department of Medicine, University of Toronto, Toronto, Ontario, Canada PubMed articles Google scholar articles
Kathleen D Liu Department of Anesthesiology, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Michael A Matthay Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Lorraine B Ware Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA PubMed articles Google scholar articles
Carolyn S Calfee Department of Anesthesiology, University of California San Francisco, San Francisco, California, USA Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, California, USA Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles

Correspondence to Dr Pratik Sinha; p.sinha{at}wustl.edu

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Citation

Sinha P, Delucchi KL, Chen Y, et al

Latent class analysis-derived subphenotypes are generalisable to observational cohorts of acute respiratory distress syndrome: a prospective study

Thorax 2022;77:13-21.

Publication history

Received February 26, 2021
Accepted June 1, 2021
First published July 12, 2021.

Online issue publication

September 01, 2022

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