Article Text

Download PDFPDF
MRI in interstitial lung disease (M-ILD): a momentum to innovate lung diagnostic
  1. Pierluigi Ciet1,2
  1. 1 Radiology and Nuclear Medicine, Erasmus MC - Sophia Children's Hospital, Rotterdam, Zuid-Holland, Netherlands
  2. 2 Pediatric Pulmonology, Erasmus MC - Sophia Children's Hospital, Rotterdam, Zuid-Holland, Netherlands
  1. Correspondence to MD, PhD Pierluigi Ciet, Radiology and Nuclear Medicine, Erasmus MC - Sophia Children's Hospital, Rotterdam, Zuid-Holland, Netherlands; p.ciet{at}erasmusmc.nl

Statistics from Altmetric.com

The prevalence of interstitial lung disease (ILD) is high and progressively increasing.1 Mortality and morbidity vary according to ILD subtype, but overall median survival is poor, ranging from 5 to 14 years.2 Irrespective of classification and cause of lung fibrosis, several patients present with progressive-fibrosing ILD (PF-ILD), characterised by a rapid decline in lung function.3

A recent landmark study demonstrated a reduction in PF-ILD disease progression using costly antifibrotic drugs.4 However, half of patients with ILD do not benefit from these expensive antifibrotic drugs but could be better treated with anti-inflammatory or combined treatment. Hence, there is an unmet need for a monitoring tool to phenotype patients with ILD by assessing the amount of pulmonary fibrosis and inflammation to guide treatment choices and monitor response.3

Current monitoring, namely, high-resolution CT (HRCT) and pulmonary function …

View Full Text

Footnotes

  • Collaborators Piotr Wielopolski, Radiology and Nuclear Medicine Department, Erasmus MC.

  • Contributors I’ve personally written the editorial.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles