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Rectal organoid morphology analysis (ROMA) as a promising diagnostic tool in cystic fibrosis

Authors

  • Senne Cuyx Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • Anabela Santo Ramalho Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • Nikky Corthout VIB Bio Imaging Core, VIB KU Leuven Center for Brain & Disease Research, Leuven, Belgium Department for Neuroscience, KU Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • Steffen Fieuws Interuniversity Center for Biostatistics and Statistical Bioinformatics, KU Leuven, Leuven, Flanders, Belgium Interuniversity Center for Biostatistics and Statistical Bioinformatics, Hasselt University, Hasselt, Limburg, Belgium PubMed articlesGoogle scholar articles
  • Eva Fürstová Department of Pediatrics, 2nd Faculty of Medicine, Motol University Hospital, Praha, Czech Republic PubMed articlesGoogle scholar articles
  • Kaline Arnauts Department of Chronic Diseases and Metabolism (CHROMETA), Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Leuven, Flanders, Belgium Department of Development and Regeneration, Stem Cell Institute Leuven (SCIL), KU Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • Marc Ferrante Department of Chronic Diseases and Metabolism (CHROMETA), Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Leuven, Flanders, Belgium Department of Gastroenterology and Hepatology, University Hospital of Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • Catherine Verfaillie Department of Development and Regeneration, Stem Cell Institute Leuven (SCIL), KU Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • Sebastian Munck VIB Bio Imaging Core, VIB KU Leuven Center for Brain & Disease Research, Leuven, Belgium Department for Neuroscience, KU Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • Mieke Boon Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • Marijke Proesmans Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • Lieven Dupont Department of Chronic Diseases, Metabolism and Ageing; Pneumology, University Hospital of Leuven, Leuven, Flanders, Belgium Department of Respiratory Diseases, University Hospital of Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • Kris De Boeck Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • François Vermeulen Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium PubMed articlesGoogle scholar articles
  • On behalf of the Belgian Organoid Project
    Google scholar articles
  1. Correspondence to Dr François Vermeulen, Department of Development and Regeneration, Woman and Child Unit, CF research lab, KU Leuven, Leuven, Flanders, Belgium; francois.vermeulen{at}uzleuven.be
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Citation

Cuyx S, Ramalho AS, Corthout N On behalf of the Belgian Organoid Project, et al
Rectal organoid morphology analysis (ROMA) as a promising diagnostic tool in cystic fibrosis
Thorax 2021;76:1146-1149.

Publication history

  • Received October 13, 2020
  • Revised February 3, 2021
  • Accepted March 9, 2021
  • First published April 15, 2021.
Online issue publication 
September 01, 2022

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© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.