Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis

Delphine Guillotin; Adam R Taylor; Manuela Platé; Paul F Mercer; Lindsay M Edwards; Ross Haggart; Gino Miele; Robin J McAnulty; Toby M Maher; Robert E Hynds; Mariam Jamal-Hanjani; Richard P Marshall; Andrew J Fisher; Andy D Blanchard; Rachel C Chambers

doi:10.1136/thoraxjnl-2020-214902

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Respiratory research

Original research

Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis

Authors

Delphine Guillotin Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK PubMed articles Google scholar articles
Adam R Taylor Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK PubMed articles Google scholar articles
Manuela Platé Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK PubMed articles Google scholar articles
Paul F Mercer Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK PubMed articles Google scholar articles
Lindsay M Edwards Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK PubMed articles Google scholar articles
Ross Haggart Epistem Ltd, Manchester, UK PubMed articles Google scholar articles
Gino Miele Epistem Ltd, Manchester, UK PubMed articles Google scholar articles
Robin J McAnulty Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK PubMed articles Google scholar articles
Toby M Maher National Heart and Lung Institute, Imperial College London, London, UK PubMed articles Google scholar articles
Robert E Hynds Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, UK PubMed articles Google scholar articles
Mariam Jamal-Hanjani Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, UK PubMed articles Google scholar articles
Richard P Marshall Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK PubMed articles Google scholar articles
Andrew J Fisher Newcastle Fibrosis Research Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK Institute of Transplantation, Newcastle Upon Tyne Hospitals, Newcastle Upon Tyne, UK PubMed articles Google scholar articles
Andy D Blanchard Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK PubMed articles Google scholar articles
Rachel C Chambers Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK PubMed articles Google scholar articles

Correspondence to Dr Rachel C Chambers, Centre for Inflammation and Tissue Repair, UCL Respiratory, UCL, London, UK; r.chambers{at}ucl.ac.uk

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Citation

Guillotin D, Taylor AR, Platé M, et al

Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis

Thorax 2021;76:73-82.

Publication history

Received March 30, 2020
Revised September 10, 2020
Accepted September 11, 2020
First published November 19, 2020.

Online issue publication

December 15, 2020

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