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Images in Thorax
Vaping-associated lung injury
  1. Orla O'Carroll1,2,
  2. Keshav Sharma3,
  3. Aurelie Fabre4,
  4. David J Murphy5,
  5. Michael P Keane1,2,
  6. Cormac McCarthy1,2
  1. 1 Respiratory Medicine, St. Vincent's University Hospital, Dublin, Ireland
  2. 2 School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
  3. 3 Department of Medicine, Wexford General Hospital, Wexford, Ireland
  4. 4 Histopathology, St. Vincent's University Hospital, Dublin, Ireland
  5. 5 Radiology, St. Vincent's University Hospital, Dublin, Ireland
  1. Correspondence to Dr Cormac McCarthy, Medicine, University College Dublin, Dublin 4, Ireland; cormac.mccarthy{at}

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An 18-year-old man presented to the emergency department of a community hospital with a cough, fever, night sweats and significant weight loss. He recently completed an antibiotic course for a lower respiratory-tract infection. Full blood count revealed a normal total white cell count with eosinophil count of 0.85×109/L. C-reactive protein (CRP) was normal but erythrocyte sedimentation rate (ESR) was 100 mm/hour. Chest radiograph demonstrated bilateral perihilar reticulonodular opacification with peripheral sparing (figure 1A). Immunoglobulin E was mildly elevated at 175UI/mL; other immunoglobulin levels, viral and autoantibody panels were normal. High-resolution CT thorax revealed diffuse centrilobular and peribronchovascular ground-glass opacification throughout both lungs with subpleural sparing (figure 1B/C). On further questioning, the patient disclosed a history of extensive vaping in the preceding 6 months including nicotine and tetrahydrocannabinol-containing products. He was referred to a specialist …

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  • OO and KS are joint first authors.

  • Twitter @keshavs21

  • Contributors All authors contributed to the conception, data collection and writing of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement Data are available upon request.

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