Oral nitrate supplementation to enhance pulmonary rehabilitation in COPD: ON-EPIC a multicentre, double-blind, placebo-controlled, randomised parallel group study

Matthew J Pavitt; Rebecca Jayne Tanner; Adam Lewis; Sara Buttery; Bhavin Mehta; Helen Jefford; Katrina J Curtis; Winston A S Banya; Syed Husain; Karnan Satkunam; Dinesh Shrikrishna; William Man; Michael I Polkey; Nicholas S Hopkinson

doi:10.1136/thoraxjnl-2019-214278

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Chronic obstructive pulmonary disease

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Oral nitrate supplementation to enhance pulmonary rehabilitation in COPD: ON-EPIC a multicentre, double-blind, placebo-controlled, randomised parallel group study

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Matthew J Pavitt National Heart and Lung Institute, Royal Brompton Campus, Imperial College London, London, UK PubMed articles Google scholar articles
Rebecca Jayne Tanner National Heart and Lung Institute, Royal Brompton Campus, Imperial College London, London, UK PubMed articles Google scholar articles
Adam Lewis National Heart and Lung Institute, Royal Brompton Campus, Imperial College London, London, UK PubMed articles Google scholar articles
Sara Buttery National Heart and Lung Institute, Royal Brompton Campus, Imperial College London, London, UK PubMed articles Google scholar articles
Bhavin Mehta Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Helen Jefford Greenwich Adult Community Health Service, Oxleas NHS Foundation Trust, Dartford, Kent, UK PubMed articles Google scholar articles
Katrina J Curtis National Heart and Lung Institute, Royal Brompton Campus, Imperial College London, London, UK PubMed articles Google scholar articles
Winston A S Banya National Heart and Lung Institute, Royal Brompton Campus, Imperial College London, London, UK PubMed articles Google scholar articles
Syed Husain Respiratory Medicine, Maidstone and Tunbridge Wells NHS Trust, Maidstone, Kent, UK PubMed articles Google scholar articles
Karnan Satkunam Greenwich Adult Community Health Service, Oxleas NHS Foundation Trust, Dartford, Kent, UK PubMed articles Google scholar articles
Dinesh Shrikrishna Musgrove Park Hospital, Taunton and Somerset NHS Foundation Trust, Taunton, Somerset, UK PubMed articles Google scholar articles
William Man National Heart and Lung Institute, Royal Brompton Campus, Imperial College London, London, UK Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Michael I Polkey National Heart and Lung Institute, Royal Brompton Campus, Imperial College London, London, UK Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Nicholas S Hopkinson National Heart and Lung Institute, Royal Brompton Campus, Imperial College London, London, UK PubMed articles Google scholar articles

Correspondence to Dr Nicholas S Hopkinson, National Heart and Lung Institute, Royal Brompton Campus, Imperial College London, London SW3 6HP, UK; n.hopkinson{at}ic.ac.uk

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Pavitt MJ, Tanner RJ, Lewis A, et al

Oral nitrate supplementation to enhance pulmonary rehabilitation in COPD: ON-EPIC a multicentre, double-blind, placebo-controlled, randomised parallel group study

Thorax 2020;75:547-555.

Publication history

Received October 31, 2019
Revised March 23, 2020
Accepted April 15, 2020
First published May 6, 2020.

Online issue publication

September 01, 2022

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