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Rapid development of bullous lung disease: a complication of electronic cigarette use
  1. Saminder Singh Kalra,
  2. Faye Pais,
  3. Eloise Harman,
  4. Daniel Urbine
  1. Pulmonary, Critical Care and Sleep Medicine, University of Florida, Gainesville, Florida, USA
  1. Correspondence to Dr Saminder Singh Kalra, University of Florida, Gainesville, FL 32610, USA; dr_saminders{at}

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Electronic cigarettes (EC) use can result in acute lung injury with varying severity of the hypoxic respiratory failure. Spontaneous resolution can result with the cessation of EC use, although some patients with severe disease have required mechanical ventilation. We describe a previously healthy patient who presented with severe hypoxemic respiratory failure and developed a rapidly progressive bullous disease and bilateral pneumothoraces. The exponential increase in lung injury from EC use combined with limited mechanistic insights into the disease process highlights the importance of promptly recognising both the disease and its complications.

A 34-year-old man was admitted with a 1-week history of pleuritic chest pain, dyspnoea and subjective fevers. He had a 15-pack year history of smoking but …

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  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.