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Images in Thorax
Diagnostic challenge of intrathoracic tissue misplacements: a thymic choristoma in a fetal lung
  1. Gianluca Lopez1,2,
  2. Roberto Croci1,2,
  3. Tommaso Rizzuti2,
  4. Stefano Ferrero1,2,
  5. Nicola Fusco1,2
  1. 1 Universita degli Studi di Milano, Milano, Italy
  2. 2 Division of Pathology, Fondazione IRCCS Ca’ Granda – Ospedale Maggiore Policlinico, Milan, Italy
  1. Correspondence to Dr Nicola Fusco, Universita degli Studi di Milano, Milano 20100, Italy; nicola.fusco{at}

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Choristomas (Gr. chōristos, ‘separated’) are well-delimited formations consisting of histologically normal tissue located in an abnormal anatomical site.1 Their aetiology is related to failures in the normal course of embryonic development of the neural tube. While choristomas are frequently encountered in some parts of the body (eg, thyroid gland, pelvis), an intrapulmonary localisation is rarer. In particular, the presence of thymic tissue in the lung has never been documented in the English literature. Here, we illustrate a choristoma composed of mature thymic tissue in the lung of a fetus who died after 16 weeks of gestation.

Case presentation

A 21-year-old, gravida 1, para 0 woman experienced a spontaneous abortion at 16 weeks of gestation. Autoptic examination of …

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  • Contributors GL and NF conceived the project. TR performed the initial diagnosis. SF and NF supervised the study. Image processing by GL. GL and RC wrote the first draft of the manuscript which was initially reviewed by NF. Subsequently, all authors contributed to and approved the final version of the manuscript. NF is the guarantor of this manuscript, taking full responsibility for its contents.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.