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Dieulafoy’s disease with mediastinal arteriovenous malformation
  1. Andrea Zhi Xin Foo1,
  2. Anne Ann Ling Hsu2
  1. 1 Monash School of Medicine, Monash University, Melbourne, Australia
  2. 2 Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore
  1. Correspondence to Dr Anne Ann Ling Hsu, Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore 169856, Singapore; anne.hsu.a.l{at}

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A 42-year-old, non-smoker man was hospitalised for newly diagnosed acute myeloid leukaemia and had an episode of haemoptysis of 200 mL fresh blood, complicated by transient hypotension. Patient was afebrile and his blood results were: haemoglobin 10.0 g/dL decreasing to 8.5 g/dL within 1 day of haemoptysis, total white cell counts 23x109/L, platelet counts 30x109/L, normal renal panel and coagulation profile. CT scan reported extensive tortuous mediastinal vessels (figure 1A). Flexible bronchoscopy under platelet transfusion revealed a small lesion in the right upper lobe (RUL) bronchus (figure 2). Upon contact of the bronchoscope tip with the lesion, brisk bleeding occurred (online supplementary video) which ceased with ice-cold saline wash. A diagnosis of Dieulafoy’s disease associated with mediastinal arteriovenous malformation (AVM) was made. CT angiogram followed by embolisation of major vessels feeding into RUL (figures 1B …

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  • Contributors The article was conceived by AZXF and AALH. AALH provided materials for the article while AZXF was responsible for the draft preparation and revision. Both authors were involved in reviewing each draft and approving the final manuscript. AALH is the guarantor of the study.

  • Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Next of kin consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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