Responses

Download PDFPDF
Original article
Environmental exposures and systemic hypertension are risk factors for decline in lung function
Compose Response

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Statement of Competing Interests

PLEASE NOTE:

  • A rapid response is a moderated but not peer reviewed online response to a published article in a BMJ journal; it will not receive a DOI and will not be indexed unless it is also republished as a Letter, Correspondence or as other content. Find out more about rapid responses.
  • We intend to post all responses which are approved by the Editor, within 14 days (BMJ Journals) or 24 hours (The BMJ), however timeframes cannot be guaranteed. Responses must comply with our requirements and should contribute substantially to the topic, but it is at our absolute discretion whether we publish a response, and we reserve the right to edit or remove responses before and after publication and also republish some or all in other BMJ publications, including third party local editions in other countries and languages
  • Our requirements are stated in our rapid response terms and conditions and must be read. These include ensuring that: i) you do not include any illustrative content including tables and graphs, ii) you do not include any information that includes specifics about any patients,iii) you do not include any original data, unless it has already been published in a peer reviewed journal and you have included a reference, iv) your response is lawful, not defamatory, original and accurate, v) you declare any competing interests, vi) you understand that your name and other personal details set out in our rapid response terms and conditions will be published with any responses we publish and vii) you understand that once a response is published, we may continue to publish your response and/or edit or remove it in the future.
  • By submitting this rapid response you are agreeing to our terms and conditions for rapid responses and understand that your personal data will be processed in accordance with those terms and our privacy notice.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

Other responses

Jump to comment:

  • Published on:
    The effect of living at high altitude and living in urban settings on lung function decline
    • Dinh S Bui, Epidemiologist School of population and global health, the University of Melbourne
    • Other Contributors:
      • Caroline J Lodge, Epidemiologist

    We read with interest the findings of Miele et al. on the relationship between environmental exposures and decline in lung function (1). The authors reported that living in urban settings and living at high altitude were associated with accelerated decline in pre-bronchodilator FEV1 and FVC. Investigating the effects at area level is important from a public health perspective and extra analysis on this valuable dataset as suggested below will help to untangle these links further.
    Study participants were recruited from four settings in Peru: Lima, Tumbles, urban Puno and rural Puno (1). Urban living and high-altitude dwelling (as binary variables) were defined based on these four settings. The authors compared the effect of urban living (Lima and urban Puno) with rural living (Tumbes and rural Puno); and the effect of high-altitude dwelling (urban Puno and rural Puno) with low-altitude dwelling (Lima and Tumbes). It is possible that the observed independent effects found by the authors of urban living and high-altitude dwelling may be driven by the urban Puno group (high altitude and urban living). In other words, there may be an interaction between urban living and high-altitude dwelling and investigating this potential interaction would be informative.
    As discussed by the authors, the adverse effect of high-altitude dwelling on lung function decline may partly be related to hypoxia and adverse effects from living in urban settings may be related to outdoor air...

    Show More
    Conflict of Interest:
    None declared.