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A 38-year-old previously fit smoker of 10 pack-years presented with 1 month of progressive worsening exertional dyspnoea. He had no cough, chest pain nor constitutional symptoms. Auscultation of the chest revealed widespread crepitations. Oxygen saturation was 96% on room air, desaturating to 88% after mild exertion. Chest radiograph showed diffuse nodular interstitial infiltrates with significant peribronchial cuffing. CT thorax revealed multiple Cheerio signs of varying sizes and wall thickness, distributed evenly bilaterally (figure 1). There was significant interlobular septal thickening with thickened peribronchovascular bundles, and a thick-walled cavitation in the left lower lobe. Flexible bronchoscopy was performed under fluoroscopy via endotracheal tube. Radial endobronchial ultrasound (R-EBUS) examination at all visible subsegmental branches of the lateral segment of the right lower lobe demonstrated multiple scattered hyperechoic linear arcs and dots, representing patent airspaces (figure 2A,B, arrow). Transbronchial lung cryobiopsy was performed uneventfully at the site of the R-EBUS examination. Histopathological examination revealed invasive lung adenocarcinoma with predominantly micropapillary and …
Contributors SSK initiated the idea for case reporting and prepared the final copy of the manuscript. MCY is the first assistant of the bronchoscopic procedure and SKC was involved in the overall patient management. STT performed the transbronchial lung cryobiopsy and supervised and reviewed the final manuscript. All authors have read and approved the final manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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