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Critical care
Original article
Metabolic phenotype of skeletal muscle in early critical illness

Authors

  • Zudin A Puthucheary Institute for Sport, Exercise and Health, University College London, London, UK Department of Medicine, Centre for Human Health and Performance, University College London, London, UK Intensive Care Unit, Royal Free London NHS Foundation Trust, London, UK Centre for Human and Applied Physiological Sciences, King’s College London, London, UK PubMed articlesGoogle scholar articles
  • Ronan Astin Institute for Sport, Exercise and Health, University College London, London, UK Department of Medicine, Centre for Human Health and Performance, University College London, London, UK PubMed articlesGoogle scholar articles
  • Mark J W Mcphail Hepatology and Gastroenterology, St Mary’s Hospital, Imperial College London, London, UK Institute of Liver Studies, Kings College Hospital NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • Saima Saeed Wolfson Institute Centre for Intensive Care Medicine, University College London, London, UK PubMed articlesGoogle scholar articles
  • Yasmin Pasha Hepatology and Gastroenterology, St Mary’s Hospital, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Danielle E Bear Centre for Human and Applied Physiological Sciences, King’s College London, London, UK Department of Nutrition and Dietetics, Guy’s and St Thomas' NHS Foundation Trust, London Department of Critical Care, Guy’s and St Thomas' NHS Foundation Trust, London Lane Fox Clinical Respiratory Physiology Research Centre, St Thomas’ Hospital, Guy’s and St Thomas’ Foundation Trust, London, London, UK PubMed articlesGoogle scholar articles
  • Despina Constantin Medical Research Council/Arthritis Research UK Centre for Musculoskeletal Aging Research, National Institute for Health Research Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK PubMed articlesGoogle scholar articles
  • Cristiana Velloso Centre for Human and Applied Physiological Sciences, King’s College London, London, UK PubMed articlesGoogle scholar articles
  • Sean Manning Centre for Obesity Research, University College London, London, UK National Institute of Health Research, UCLH Biomedical Research Centre, University College London Hospitals, London School of Medicine, University College Cork, Cork, Ireland PubMed articlesGoogle scholar articles
  • Lori Calvert Northwest Anglia foundation Trust, Peterborough City Hospital NHS Trust, Peterborough, UK PubMed articlesGoogle scholar articles
  • Mervyn Singer Intensive Care Unit, Royal Free London NHS Foundation Trust, London, UK Wolfson Institute Centre for Intensive Care Medicine, University College London, London, UK PubMed articlesGoogle scholar articles
  • Rachel L Batterham Centre for Obesity Research, University College London, London, UK National Institute of Health Research, UCLH Biomedical Research Centre, University College London Hospitals, London PubMed articlesGoogle scholar articles
  • Maria Gomez-Romero Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, London, UK PubMed articlesGoogle scholar articles
  • Elaine Holmes Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, London, UK PubMed articlesGoogle scholar articles
  • Michael C Steiner Institute for Lung Health, Leicester NIHR Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK PubMed articlesGoogle scholar articles
  • Philip J Atherton Medical Research Council/Arthritis Research UK Centre for Musculoskeletal Aging Research, National Institute for Health Research Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK PubMed articlesGoogle scholar articles
  • Paul Greenhaff Medical Research Council/Arthritis Research UK Centre for Musculoskeletal Aging Research, National Institute for Health Research Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK PubMed articlesGoogle scholar articles
  • Lindsay M Edwards Digital, Data & Analytics Unit, Respiratory Therapy Area, GlaxoSmithKline Medicines Research Centre, Stevenage, UK PubMed articlesGoogle scholar articles
  • Kenneth Smith Medical Research Council/Arthritis Research UK Centre for Musculoskeletal Aging Research, National Institute for Health Research Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK PubMed articlesGoogle scholar articles
  • Stephen D Harridge Centre for Human and Applied Physiological Sciences, King’s College London, London, UK PubMed articlesGoogle scholar articles
  • Nicholas Hart Lane Fox Clinical Respiratory Physiology Research Centre, St Thomas’ Hospital, Guy’s and St Thomas’ Foundation Trust, London, London, UK Lane Fox Respiratory Service, St Thomas’ Hospital, Guy’s and St Thomas’ Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • Hugh E Montgomery Institute for Sport, Exercise and Health, University College London, London, UK Department of Medicine, Centre for Human Health and Performance, University College London, London, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Zudin A Puthucheary, Institute for Sport, Exercise and Health, University College London, London W1T 7HA, UK; zudin.puthucheary.09{at}ucl.ac.uk
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Citation

Puthucheary ZA, Astin R, Mcphail MJW, et al
Metabolic phenotype of skeletal muscle in early critical illness
Thorax 2018;73:926-935.

Publication history

  • Received September 23, 2017
  • Revised May 17, 2018
  • Accepted May 28, 2018
  • First published July 6, 2018.
Online issue publication 
September 01, 2022

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.